Endometriosis Test In Dubai – EndoTest

No. Endotest requires a saliva sample, so there are no needles, injections, anaesthetic or surgical instruments. Collection usually takes only a few minutes and is not expected to cause pain or physical side effects. The main issue is obtaining a sample that meets the laboratory’s quality requirements. Food, toothpaste, lipstick, tobacco, chewing gum, blood or nasal secretions can contaminate saliva and may mean that a new sample is needed. Tell the clinic if you have significant dry mouth, an oral problem or an infection on the collection day. The team will explain the collection steps and confirm whether testing should proceed or be postponed.

Endotest has shown high diagnostic performance, but it should not be described as identical to laparoscopy. A 2025 manufacturer-funded prospective multicentre validation study of 971 symptomatic patients aged 18–43 reported 96.6% overall accuracy, 97.3% sensitivity and 94.1% specificity in that study cohort. These figures may not apply equally to asymptomatic people or populations with a different likelihood of endometriosis, and false-positive and false-negative results remain possible. Laparoscopy serves a different purpose: it allows a surgeon to inspect the pelvis, take a biopsy when appropriate and sometimes treat visible disease during the same procedure. Endotest provides molecular diagnostic information from saliva but cannot show lesion location, depth or surgical anatomy. Your gynaecologist should interpret it alongside symptoms, examination and imaging.

Endotest analyses a signature of salivary microRNAs using next-generation sequencing and an algorithm, producing molecular evidence that supports or argues against an endometriosis diagnosis. Specialist transvaginal ultrasound and pelvic MRI examine anatomy: they can identify ovarian endometriomas and many forms of deep endometriosis, assess organs that may be involved and help plan surgery. Imaging can be normal when superficial disease is present, but Endotest does not replace the anatomical information imaging provides. It cannot map lesions, measure their size, assess adhesions or determine whether the bowel, bladder or ureters are affected. The tests are therefore complementary. The appropriate sequence depends on symptoms, examination findings, previous imaging, fertility plans and whether medical or surgical treatment is being considered.

A positive result supports the presence of endometriosis, but it does not reveal the stage, location or severity of disease and does not automatically mean that surgery is required. Dr Anna Sepiolo will review the result with your symptoms, examination, previous ultrasound or MRI, medications, fertility goals and the effect on daily life. Depending on the clinical picture, next steps may include specialist imaging, symptom-directed medical treatment, pain management, fertility advice or referral to an endometriosis surgeon or multidisciplinary team. Laparoscopy may still be considered when imaging is inconclusive, symptoms persist despite treatment, deep disease is suspected or surgery is likely to change management. Other possible causes of pelvic pain, painful periods, bowel or bladder symptoms and infertility should also be evaluated.

Yes—Endotest is intended for patients aged 18–43 who have symptoms suggestive of endometriosis, rather than as a general screening test for people without symptoms. Relevant concerns can include persistent pelvic pain, severe period pain, deep pain during sex, painful bowel movements or urination, cyclical rectal bleeding or blood in the urine, shoulder-tip pain linked to menstruation, or otherwise unexplained infertility. Symptoms may be subtle, variable or occur outside menstruation, so an assessment is still worthwhile when the pattern is unclear. According to the manufacturer, testing is contraindicated during pregnancy and in people with a history of cancer or HIV, or an infection at the time of collection. A clinician must confirm that the test is appropriate and interpret the result in context.

No. Endotest is designed to indicate whether a salivary microRNA pattern is consistent with endometriosis; it does not produce an anatomical map or assign a surgical stage. A positive result cannot tell whether disease is superficial, ovarian or deep, which organs may be affected, how extensive adhesions are, or whether a particular lesion is responsible for pain or infertility. Specialist ultrasound or MRI may therefore still be required, especially when an ovarian endometrioma or deep disease involving the bowel, bladder or ureters is suspected. If surgery is being considered, imaging helps the clinical team plan the procedure and involve the appropriate specialists. Disease stage also does not always correlate with symptom severity, so treatment decisions should focus on symptoms, anatomy, fertility goals and patient preferences.

A negative result makes endometriosis less likely, but no diagnostic test is perfect. In the 2025 validation cohort, the negative predictive value was 91.3%; this value changes according to how common endometriosis is in the population being tested. A false-negative result is therefore possible, and a negative Endotest should not be used by itself to dismiss persistent or severe symptoms. Your doctor may reconsider other causes of pelvic pain, abnormal bleeding, bowel or bladder symptoms, painful sex or infertility, and may recommend specialist ultrasound, MRI, treatment review or—in selected cases—laparoscopy. Seek reassessment if symptoms continue, worsen or affect quality of life. The result is one part of a clinical evaluation, not a substitute for follow-up or safety assessment.

According to the manufacturer’s intended-use information, Endotest can be performed while using hormonal treatment and at any point in the menstrual cycle. Do not stop the contraceptive pill, progestogen, hormonal coil, GnRH treatment or any other prescribed medicine simply to take the test unless your treating clinician specifically advises it. Provide a complete list of medications and tell the clinic about pregnancy, current infection, recent procedures and relevant medical history so that eligibility and timing can be checked. Blood or nasal secretions in the saliva sample can affect sample quality, so carefully follow the collection instructions and inform the team if oral bleeding is present. If the sample is unsuitable, recollection may be required.

Follow the exact instructions supplied with the collection kit and by EV Clinic, because good sample quality is essential for RNA analysis. The saliva must not contain food, toothpaste, lipstick, tobacco, chewing-gum residue, blood or nasal secretions. Avoid eating, drinking, smoking, chewing gum, brushing your teeth or applying lip products for the period specified in the kit instructions, and postpone collection if the clinic advises this because of an infection or oral bleeding. The sample is stabilised and sent to a specialised laboratory for sequencing and algorithmic analysis. The page’s usual estimated turnaround is approximately two to three weeks, although transport, laboratory processing or the need to recollect an unsuitable sample may affect timing. The clinic will arrange interpretation rather than treating the report as a stand-alone result.

The cost of an Endotest in Dubai may include the medical consultation, saliva-collection kit, sample handling and international laboratory processing, sequencing and analysis, and a follow-up appointment to explain the result. The final price can therefore differ from a standard laboratory test and should be confirmed directly with EV Clinic before booking. Ask whether the quotation includes the initial assessment, the test itself, shipping, result interpretation and any recommended ultrasound, MRI or additional consultation. Insurance coverage varies by policy and indication, so patients should check reimbursement with their insurer in advance. Cost should be considered alongside eligibility, expected clinical value and how the result would change management; an experienced clinician should determine whether Endotest is the most appropriate next diagnostic step.