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PMDD (Premenstrual Dysphoric Disorder)

PMDD is a severe form of PMS with significant mood-related symptoms that impact daily functioning.

Signs and Symptoms:

  • Severe depression
  • Anxiety
  • Irritability, anger
  • Fatigue
  • Insomnia
  • Depression, feelings of hopelessness
  • Anxiety, tension
  • Breast tenderness
  • Joint pain
  • Muscle pain
  • Swelling, weight gain 

Pathophysiology: Exaggerated sensitivity to normal hormonal fluctuations disrupts serotonin and GABA regulation.

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